Erectile Dysfunction,Causes Erectile Dysfunction,Erectile Dysfunction Impotence,Treat Erectile Dysfunction,Dysfunction Erectile,Erectile Dysfunction Drug - VIAGRA [Sildenafil citrate] An Overview
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VIAGRA [Sildenafil citrate] An Overview
VIAGRA [Sildenafil citrate] is the only approved and effective oral agent for the treatment of erectile dysfunction. Before that a few lines on erectile dysfunction. Erectile dysfunction [Impotence] is a condition in which erection the penis cannot be achieved during sexual intercourse/masturbation. There are many causes for erectile dysfunction. The most common cause of being increasing age. Other conditions can be: - Diabetes Mellitus - Hypertension - Heart Disease - Atherosclerosis - Lower spinal cord injury - Cancer prostate - Psychogenic - Stress Erection is achieved when there is increased blood flow to penis and hence the main organic cause is disturbance of blood flow to and from the penis. Coming back to VIAGRA [Sildenafil citrate], Viagra is a selective and potent inhibitor of cyclic guanosine monophosphate [cGMP] specific phosphodiesterase type 5 inhibitor [PDE5] which is the predominant phosphodiesterase isoform found in the penis. It is administered in doses of 25, 50 and 100 mg, and enhances erection after sexual stimulation. The onset of action is around 60-90 mins. Sildenafil (compound UK-92,480) was synthesized by a group of chemists working at Pfizer's Sandwich, Kent research facility in England. It was initially studied for use in hypertension and angina pectoris. The first clinical trials were conducted in Morriston Hospital in Swansea. Phase I clinical trials under the direction of Ian Osterloh suggested that the drug had little effect on angina, but that it could induce marked penile erections. VIAGRA [Sildenafil citrate] was approved for use in erectile dysfunction by the Food and Drug Administration on March 27, 1998, becoming the first pill approved to treat erectile dysfunction Reduced initial doses should be considered for patients, who are elderly, have renal insufficiency, or are taking medications that inhibit the CYP3A4 metabolic pathway in the liver [e.g., erythromycin, cimetidine, ketoconazole] as they may increase the serum concentration of sildenafil. The drug does not affect ejaculation, orgasm or sexual drive. When sexual stimulation causes local release of NO, inhibition of PDE5 by VIAGRA [Sildenafil citrate] causes increased levels of cGMP in the corpus cavernosum of the penis resulting in smooth muscle relaxation and inflow of blood to the corpus cavernosum. Side Effects: ?? Headaches ?? Facial flushing ?? ringing in ears, or sudden hearing loss ?? Dyspepsia ?? Nasal congestion. ?? Abnormal vision [blue halo effect] ?? Diarrhea ?? Dizziness ?? Rashes Viagra can decrease blood flow to the optic nerve of the eye, causing sudden vision loss:- Special precautions: In patients with ?? Bleeding disorders such as hemophilia ?? Liver disorder ?? Kidney disorder ?? Active peptic ulcerations and ?? Anatomical deformation of the penis, such as peyronie's disease. ?? Retinitis pigmentosa Contraindications: VIAGRA [Sildenafil citrate], is contraindicated in men receiving nitrate therapy for cardiovascular disease, including agents delivered by oral, sublingual, trans-nasal or topical routes. These agents can potentates its hypotensive effect and may result in profound shock. Viagra should be avoided in patients with congestive heart failure and cardiomyopathy because of the risk of vascular collapse.
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Kevin H. is a computerized graphic design professional from Baton Rouge, Lousiana who experienced partial, permanent blindness in his right eye within thirty nine hours after taking Viagra.
Reading on the computer is a requirement of his job, however Kevin reports that "I now read with difficulty and it is becoming harder for me to be effective in my work."
Kevin may be suffering from... 
If you are taking Erectile Dysfunction pills, have you ever wondered, "How to cure erectile dysfunctions naturally?" If you have, you are part of the millions of men who are throwing away their Viagra and switching to natural, holistic remedies. And you would be surprised how effective they are?
Taking impotence pills has almost become a norm for most men over 45 years old. A once...
Healthy sex life is one way to make life happy and contented. Many men have lost their sex life due to sickness. This sickness is called impotence. Like other chronic diseases, impotence is also incurable. There is no cure for impotence until now but it can but treated. Today's advancement in medicine has remedied the present problems of most men ages 50 and above. Tadalafil (Ciallis ) was...
Many people with impotence problems may have wondered about effective ways to deal with erectile dysfunction. Apart from drugs such as Viagra which are expensive there are herbal drugs which are available. They are manufactured from natural herbs such as Ginseng, Horny Goat Weed, Cnidium, Bombyx Mori, Schizandra berries and other herbs. These "herbal viagra" tablets are as effective as any other...
In fact, a thriving sexual interaction is considered as a way for both men and women to get all the hidden pleasure of the life. But it is not a reality for every person. There are number of couples who are incapable to get this real pleasure because of impotence. Impotence also known as Erectile Dysfunction (ED) is a condition where men are not capable to generate the desired erection to satisfy...
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